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How drugs pumped into supermarket chickens pose a terrifying threat to our health


Balasaheb Darade left US job to fight Maharashtra local polls and wins as an Independent with over 50% vote.
He lived in the US for over a decade. But the nanotechnology scientist left his cutting edge work when conscience beckoned him to help change and improve things in his deprived Parda village in the Vidarbha region.

Treading the heat and grime of grassroots politics is 28-year-old Balasaheb S. Darade, who is contesting as an independent candidate from the Pangradole constituency in the Buldhana district council polls scheduled for Feb 7.

“I am focussing on three key aspects – rural development, youth empowerment and changing the attitude of people – if they want to see change, they must change themselves,” Darade, who came back to India last year, told IANS in an interview.

Born in Parda village, 450 km southeast of Mumbai, which has now grown into a small town with around 25,000 people, Darade was educated here and in other parts of the state before joining the University of Cincinnati, US, from where he completed his masters in nanotechnology.

“I had always been keen on research, especially nano in solar cells. My work got me a consultancy assignment with US space agency NASA and I worked on the Mars Rover Project on nano solar cells,” he said.

Darade always longed to return to his town and do something for people’s upliftment – almost like Shah Rukh Khan in the movie “Swades”.

During his stay in the US till August 2011, Darade keenly watched and drummed up support for social activist Anna Hazare’s anti-corruption crusade. He also came in contact with spiritual guru Sri Sri Ravi Shankar in the US and met former president A.P.J. Abdul Kalam on several occasions.

He even formulated plans for a revamp of villages partly by incorporating Hazare’s Ralegan-Siddhi model village principles.

“I launched the Shankar Rural Transformation Project (SRTP) in 20 villages in the Vidarbha region, plagued by farmland suicides, huge unemployment and consequent problems, and depression among the people who feel they have no future,” he said.

“These personalities appreciated my efforts, inspired and encouraged me to enter politics which is abhorred and shunned by the educated class in India,” Darade told IANS while on the campaign trail.

The SRTP project – dedicated to the memory of his late parents Shankar and Ratnamala, who perished in a fire accident three years ago and his mentor, Sri Sri Ravi Shankar – has taken off with volunteers in each of the target villages.

Darade has taken up SRTP in three parts – sustainable village development projects for solving a village’s need-based problems, individual empowerment, and finally collaboration with government and other agencies.

Initially hoping to contest the state legislature elections in 2014, it was barely two weeks ago that Darade decided to take the plunge into the local body polls – which he said would enable him to study and understand deeply the problems afflicting the rural, agro-based state economy and people’s plight.

Darade has been allotted a ‘cup and saucer’ election symbol, but says he is not bothered about ‘token symbolism’. Instead, he wants to involve the masses in a big way and put them on the path to progress and prosperity.

His public meetings, with audiences ranging from groups of 20 to 8,000 (the biggest till date attended by curious farmers who decided to hear yet another speaker), have short issue-based speeches and are spiced with meditation and chanting of popular folk songs.

“I prefer quality in my meetings. Quantity or big crowds do not really get the message across,” he explained.

Though reluctant to name his main challengers, he said the biggest rivals would be the Shiv Sena with its powerful local MP Prataprao Jadhav and legislator Sanjay Raimulkar, and the Congress-Nationalist Congress Party combine.

Depending solely on public donations, volunteers’ contributions, including sympathizers from India Against Corruption (IAC), and his own meagre resources, Darade moves around in a hired vehicle, armed with his cap that says “Now Change is Certain”, which he distributes to people he meets daily.

He claims that though written off initially, he has now been flooded with messages, letters and e-mails of support. The village youth participation in his campaign has grown manifold.

“I have realised that elections, however small, are a tough job. But in a democracy, elections are a must and it is imperative to elect good representatives at all levels – I have taken the first step towards this change.”

After this experience, Darade hopes to contest the Maharashtra assembly elections due 2014.



Microscopic Image Of Mona Lisa

The Micro Lisa: Incredible 'molecular painting' of masterpiece that is three times narrower than a HUMAN HAIR

  • The tiny picture is 'painted' on a substrate that is just 30 microns in width using tiny chemical reactions
  • American scientists controlled the number of new molecules created - the greater the heat, the darker the shade of grey
  • Researchers at the Georgia Institute of Technology believe 'Mini Lisa' demonstrates a technique that could be used in nanomanufacturing
PUBLISHED: 10:00 GMT, 6 August 2013 | UPDATED: 11:52 GMT, 6 August 201


American scientists have recreated the world's most famous painting on the world's smallest canvas, which measures just 30 microns in width.
The Mona Lisa, originally painted by Leonardo da Vinci, has now been 'painted' on a substrate measuring one third of the width of a human hair, using tiny chemical reactions.
The scientists believe 'Micro Lisa' demonstrates a technique that could potentially be used to achieve nanomanufacturing of devices as they were able to vary the surface concentration of molecules on such short-length scales.
Georgia Tech researchers have created the 'Mini Lisa' on a substrate surface approximately 30 microns in width
Researchers from the Georgia Institute of Technology have created the 'Mini Lisa' on a substrate surface approximately 30 microns in width. The image demonstrates a technique that could potentially be used to achieve nano-manufacturing of devices
The Mona Lisa by Leonardo da Vinci, which is the best known and most parodied painting in the world
The Mona Lisa by Leonardo da Vinci, which is the best known and most parodied painting in the world
The famous image was re-created with an atomic force microscope and a process called ThermoChemical NanoLithography (TCNL). 
Going pixel by pixel, scientists at the Georgia Institute of Technology positioned a heated cantilever at the substrate surface to create a series of confined nanoscale chemical reactions.
 
By varying only the heat at each location, PhD Candidate Keith Carroll controlled the number of new molecules that were created - the greater the heat, the greater the local concentration. 
More heat produced the lighter shades of grey, as seen on the Mini Lisa's forehead and hands. 
Less heat produced the darker shades in her dress and hair, which can be seen when the molecular canvas is visualised using fluorescent dye. Each pixel is spaced by 125 nanometers.
Jennifer Curtis, an associate professor in the School of Physics and lead author of the study that was published in journal Langmuir, said: 'By tuning the temperature, our team manipulated chemical reactions to yield variations in the molecular concentrations on the nanoscale.
'The spatial confinement of these reactions provides the precision required to generate complex chemical images like the Mini Lisa.'
The famous image was re-created with an atomic force microscope
The famous image was re-created with an atomic force microscope (pictured) and a process called ThermoChemical NanoLithography (TCNL). Going pixel by pixel, scientists positioned a heated cantilever at the substrate surface to create a series of confined nanoscale chemical reactions
Production of chemical concentration gradients and variations on the sub-micrometre scale are difficult to achieve with other techniques.
The scientists produced chemical gradients of amine groups, but expect the process could be extended for use with other materials. 
Professor Curtis said: "We envision TCNL will be capable of patterning gradients of other physical or chemical properties, such as conductivity of graphene.
Professor Curtis (pictured) said technique should enable a wide range of previously inaccessible experiments
Professor Curtis (pictured) said technique should enable a wide range of previously inaccessible experiments and applications in fields as diverse as nanoelectronics, optoelectronics and bioengineering
'This technique should enable a wide range of previously inaccessible experiments and applications in fields as diverse as nanoelectronics, optoelectronics and bioengineering.'
She said another advantage is that atomic force microscopes are fairly common and the thermal control is relatively straightforward, making the approach accessible to both academic and industrial laboratories. 
To facilitate their vision of nano-manufacturing devices with TCNL, the Georgia Tech team has recently integrated nanoarrays of five thermal cantilevers to accelerate the pace of production. 
Because the technique provides high spatial resolutions at a speed faster than other existing methods, even with a single cantilever, Professor Curtis is hopeful that TCNL will provide the option of nanoscale printing integrated with the fabrication of large quantities of surfaces and everyday materials, whose dimensions are more than one billion times larger than the TCNL features themselves.

How drugs pumped into supermarket chickens pose a terrifying threat to our health

PUBLISHED: 00:27 GMT, 10 August 2013 | UPDATED: 00:27 GMT, 10 August 2013
Every second of every day, somewhere in the world the same scene unfolds. 
A batch of several hundred eggs, precisely arranged in uniform rows, moves along a conveyor belt, coming to a halt beneath a machine linked to a jumble of tubes.
Once in position, the machine robotically lowers itself and then simultaneously punctures each egg with a rack of hypodermic needles.
Through these needles, a mix of vaccines and antibiotics is injected into the egg — and so into the unborn chick inside, which three days later will hatch out.
Danger: Drugs being pumped into supermarket chickens are posing a threat to our health
Danger: Drugs being pumped into supermarket chickens are posing a threat to our health
If the scene sounds like something from a science-fiction film, then that is hardly a surprise. Today, large-scale poultry production has precious little to do with green fields and ruddy-cheeked farmers.
Every year, more than 40 billion chickens are slaughtered worldwide for meat, the vast majority of them intensively factory-farmed.
The bottom line is profit. All that matters is the volume in which these animals, bred to hit their genetically-modified slaughter weights within 35 days of hatching, can be churned out. 
 
Given the intensity of the production systems (raised in sheds of 50,000 birds, each will be lucky to have the space of a piece of A4 paper in which to live), the dangers of disease are massively magnified.
And so it is to prevent this that the chickens are vaccinated before birth against common diseases. 
They are often also dosed up with antibiotics — a preventative measure that is easier and cheaper than dealing with individual illnesses at a later date.
In Britain, consumers can’t get enough of cheap chicken. On average, we eat 31 kilos per person per year — which is more than any other country in Europe.
Early start: Chicks are vaccinated as soon as their eggs are laid and before they even hatch
Early start: Chicks are vaccinated as soon as their eggs are laid and before they even hatch
With a budget supermarket chicken today available for less than £2.50 per bird, cost is one of the drivers behind its ever-growing popularity. 
Not only that, but with the horsemeat scandal still fresh in consumers’ minds and the fact that chicken is lower in fat than red meat, it is also seen as a ‘healthy’ option.
How deeply ironic then that scientists now believe that the nation’s love affair with the fowl could be about to trigger a devastating health crisis of its own.
Forget the fact that last month it emerged that food poisoning cases linked to infected chicken — thanks to a bug called campylobacter — struck down 580,000 people last year, putting 18,000 in hospital and killing 140.
Now experts are warning that the overuse of antibiotics in poultry farms around the world is creating a generation of superbugs that are resistant to treatment by virtually every drug in the medical establishment’s armoury.
With up to 80 per cent of the raw chicken on sale in some countries carrying these resistant bacteria, they can be transferred to humans during the handling of infected meat or the eating of undercooked produce.
The bacteria will then survive in the gut before potentially triggering illnesses such as persistent urinary infections or, more seriously, blood poisoning, also known as sepsis.
A newly-published report claims that as a direct result of this, 1,500 lives are being lost in Europe each year — with 280 of them in this country alone.
Dietary staple: Every year, more than 40 billion chickens are slaughtered worldwide for meat, the vast majority of them intensively factory-farmed
Dietary staple: Every year, more than 40 billion chickens are slaughtered worldwide for meat, the vast majority of them intensively factory-farmed
But the fear is that, as the resistant bugs spread, the death toll will  rise as more and more antibiotics become ineffective.
‘We have people dying who do not need to die, because you should not be using these drugs in food animals at all, particularly in poultry,’ says Peter Collignon, a world authority on the subject and professor of infectious diseases at the Australian National University.
‘It is a practice we must not allow to continue, because basically there are no more antibiotics in the pipeline coming along to rescue us. The farming industry’s argument is that if they don’t do this, then one or two per cent of their flocks might die after they hatch. My view of that is “bad luck”.
‘A one or two-day-old chick that dies is worth a fraction of a penny. A human being is worth a million times more than a chicken — so we just shouldn’t do it.’
Someone who knows first-hand the dangers posed by the infections  that scientists are warning of is life coach Susie Wiggins. In March last year, the 53-year-old from Northwood, Middlesex, headed into Central London to meet a girlfriend for lunch at an upmarket restaurant.
‘We were going on to an exhibition afterwards and I was dressed up to the nines — four-inch heels, full make-up — and was feeling absolutely fine,’ she says.
‘But as we sat down for lunch I started to feel very ill, very quickly. I had unbelievable cramping in my stomach, went to the loo and when I came back I was rambling and talking nonsense.’
Realising something was seriously wrong, Miss Wiggins’ friend immediately took her to Guy’s Hospital. Within hours she was unconscious and in intensive care.
‘Basically, the pain I felt was my organs starting to shut down,’ she says. ‘I was in a coma for two weeks, during which time my hands and feet swelled up and turned black.
‘The doctors were so worried I would die that they arranged a room for my mother to stay in so she could be with me when it happened.’
That Miss Wiggins survived was down to the fact that the doctors had quickly spotted that she was suffering from sepsis. The condition strikes hard and fast and kills 37,000 people a year in the UK.
Cheap: With a budget supermarket chicken today available for less than £2.50 per bird, cost is one of the drivers behind its ever-growing popularity
Cheap: With a budget supermarket chicken today available for less than £2.50 per bird, cost is one of the drivers behind its ever-growing popularity
Treatment is with antibiotics, but one of the emerging problems today is finding the right one to use.
In Miss Wiggins’ case, it turned out that her illness was due to an E.coli infection, which could have been caused by chicken or another infected meal she had eaten at some point before that fateful lunch.
Doctors believe the bacteria may have passed through the wall of her colon into her bloodstream after she underwent colonic irrigation or as a result of infected kidney stones.
But it took them 48 hours and several antibiotics to identify the strain of the bug.
‘I was very lucky that my body held up that long,’ said Miss Wiggins. ‘In the past, it would have been much easier for the doctors, but nowadays they have to work out which antibiotic to use, which can cause delays. And with sepsis, you really don’t have much time.’
It is a point echoed by Dr Ron Daniels, chairman of the UK  Sepsis Trust and a hospital critical care consultant.
Worrying: Scientists are particularly concerned that the overuse of a certain type of antibiotic is linked to a drug resistant strain of E. Coli
Worrying: Scientists are particularly concerned that the overuse of a certain type of antibiotic is linked to a drug resistant strain of E. Coli
He says that in some parts of the country, 30 per cent of E.coli bacteria encountered are what is known as Extended-Spectrum Beta-lactamase E.coli. In layman’s terms, this  means that they are resistant to many antibiotics.
‘An ESBL E.coli is no more likely than other E.coli to cause illness but, when it does, unless we are aware that it is an ESBL E.coli there is a danger we might start treating with antibiotics to which the bacteria is resistant,’ he explains.
‘The problem is that if we do that, that would be as ineffective as not treating with antibiotics at all.’
At least today there are a handful of antibiotics out there that still work. The big concern is that if resistance continues to spread, there will simply be no antibiotics left that can be effectively deployed.
If that happens, then the 21st century could see the death toll from infections soar to 19th-century levels.
It is a point that was made earlier this year by Dame Sally Davies, the Chief Medical Officer, who warned that antibiotic-resistant bacteria posed ‘a catastrophic threat’ to  the population.
‘If we don’t act now, any one of us could go into hospital in 20 years for minor surgery and die because of an ordinary infection that can’t be treated by antibiotics,’ she said.  
‘And routine operations like hip replacements or organ transplants could be deadly because of the risk of infection.’
In the past, the blame for the growth of drug-resistant superbugs was pinned on doctors who over- prescribed antibiotics to patients.
But there is a growing body of opinion that believes excessive use of the drugs within the agricultural world — especially cheap chicken — is equally to blame.
Scientists are particularly  concerned about the over-use of a group of antibiotics called cephalosporins, which they believe are linked to the emergence of drug-resistant strains of E.Coli.
Cephalosporins are a class of antibiotics that the World Health Organisation has rated as ‘critically important to human medicine’.
‘For me the evidence is overwhelming,’ says Professor Collignon. ‘With certain bacteria, what we do with animals is making them resistant.’ 
He explains that of all the antibiotics used in the world, about 80  per cent are used on food animals, about 15 to 20 per cent on patients in the community, and just five per cent in hospitals. 
‘What we know is that there is an epidemic of these resistant E.coli in Europe causing bloodstream infections,’ he says.
‘What is interesting is that these bacteria are resistant to antibiotics that we do not give widely in the community — only in hospitals.
Health risk: Food poisoning cases linked to infected chicken ¿ thanks to a bug called campylobacter ¿ struck down 580,000 people last year, putting 18,000 in hospital and killing 140
Health risk: Food poisoning cases linked to infected chicken ¿ thanks to a bug called campylobacter ¿ struck down 580,000 people last year, putting 18,000 in hospital and killing 140
‘So to me the available evidence suggests that a reasonable proportion of these are coming through food, with poultry a particular risk.’
In a study published last week in the Journal for Infectious Diseases, Professor Collignon and other scientists highlighted data from Holland which showed that 56 per cent of antibiotic-resistant E.coli genes in human blood-poisoning cases were identical to E.coli genes from retail chicken samples.
The transmission of one particularly resistant strain of EDSL E.coli tripled between people and animals from 2007 to 2012, the report claimed. 
Extrapolating the Dutch data to other European countries, it estimated the number of deaths caused by antibiotic-resistant  E.coli associated with chicken is 62 in France; 115 in Italy; 192 in Germany and 282 in Britain.
As well as 1,518 extra deaths Europe-wide, that also equated to an extra 67,236 days of hospital admissions.
‘The number of avoidable deaths and the costs of healthcare potentially caused by cephalosporin use in food animals is staggering,’ the scientists concluded.
‘Considering these factors, the ongoing use of these anti-microbial drugs . . . should be urgently examined and stopped, particularly in poultry, not only in Europe,  but worldwide.’
Fear: Up to 80 per cent of the raw chicken on sale in some countries carries drug resistant bacteria, and they can be transferred to humans during the handling of infected meat or the eating of undercooked produce
Fear: Up to 80 per cent of the raw chicken on sale in some countries carries drug resistant bacteria, and they can be transferred to humans during the handling of infected meat or the eating of undercooked produce
Interestingly, it appears that the less-intensively reared the chicken, the more reduced the likelihood of creating resistant bacteria.
Chickens that are organically raised are likely to come into far less contact with antibiotics. The use of the drugs in organic animals is restricted to when they are ill, and even then only when  there are no alternative treatments available.
Research in 2006 compared E.coli samples taken from organic and non-organic farm animals, observing their resistance to ten different types of antibiotic.
On average, those from organic farms were resistant to one antibiotic, compared with five on non-organic farms.
But, of course, that comes at a price. An organic chicken on sale in a supermarket will cost at least two-and-a-half times more than the cheapest ‘budget’ chicken.
Unsurprisingly, poultry farmers have reacted angrily to being blamed for the crisis.
A spokeswoman for The British Poultry Council dismissed the study as ‘alarmist’ and said that it was based on out-of-date research.
She said: ‘Extrapolating the calculations of possible human deaths from the Netherlands to the UK was flawed from the outset, because antibiotics were used differently in UK poultry production . . . when compared to how they were used in the Netherlands.’
Cephalosporins, she explained, had never been administered in flocks used for meat production here.
And while they had been used in the breeding flocks, which produce the eggs that then hatch into meat chickens, the industry had voluntarily agreed to stop all use at the end of 2011.
‘British consumers can be assured that British chickens are reared according to the strict production standards of the Red Tractor assurance scheme,’ she said.
‘These standards include rigorous controls of the use of medicine under veterinary supervision. All medicines on farms should be used as little as possible and only as much as necessary.
‘We’re strongly committed to a prudent and responsible use of antibiotics in poultry and all other livestock and will continue to engage with the government, the livestock sector and other stakeholders on this matter.’
But critics are unconvinced and say that even the limited use in the breeding flocks could have been potentially problematic, with resistance being passed down through generations of chickens.
And they also point out that whatever native farmers are doing, Britain imports large quantities of chicken meat from abroad.
While 1.3   million tonnes of chicken meat is reared here (the equivalent of 900 million chickens a year), a further 700,000 tonnes is imported.
Worryingly, Holland is the biggest source of these imports, followed by Thailand — a country where concerns have been raised about the widespread use of antibiotics.
Given the growing taste for chicken in this country, it means that international action against antibiotic overuse is essential.
In the meantime, efforts are finally being taken to better understand what is behind the spread of these antibiotic-resistant E.coli.
Last month, the Government launched a three-year study into the problem. It will involve collecting ESBL E.coli samples from farm slurry and from raw meat on sale to the public.
This will then be compared with samples taken from human blood and faecal samples to see what genetic similarities there are between the two.
While scientists welcome the study, they warn that we cannot sit back and wait for the results before taking action.
Time, they say, is critical — something that Susie Wiggins knows to be the case from her own, terrifying, experience.


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